MOLECULAR BIOLOGY • PROTEIN ENZYMES

Proteinase K (Lyophilized Powder)

Highly active recombinant Proteinase K for nucleic acid extraction, molecular diagnostics, genetic testing, and biopharmaceutical sample preparation.

CAT#  1012-HH4500-01
SIZE  0.1 g
DRY ICE  No
HAZARDOUS  No
PRODUCT INFORMATION

Proteinase K Lyophilized Powder

Recombinant serine protease derived from Tritirachium album, designed for efficient protein digestion in nucleic acid purification, molecular diagnostics, and biological sample preparation workflows.

CATALOG NUMBER
1012-HH4500-01
PACKAGE SIZE
0.1 g
DRY ICE
No
AVAILABILITY
Research Supply
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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PRODUCT DESCRIPTION

High-Activity Proteinase K for Molecular Biology

Proteinase K is a highly active recombinant serine protease derived from Tritirachium album, widely used in nucleic acid extraction, molecular diagnostics, and biopharmaceutical sample preparation. It exhibits broad substrate specificity and efficiently digests proteins under both native and denaturing conditions, including in the presence of detergents such as SDS and urea.

Developed through directed evolution technology, Proteinase K provides enhanced enzymatic activity, stability, and compatibility with nucleic acid purification workflows. The product is free of detectable DNase, RNase, and nickase contamination, supporting sensitive DNA and RNA applications.

TECHNICAL DATA

Product Specifications

Appearance
White to off-white amorphous powder, lyophilized
Activity
≥30 U/mg
DNase
None detected
RNase
None detected
Nickase
None detected
APPLICATIONS

Proteinase K Applications

01

DNA & RNA Extraction

Efficiently degrades proteins and nucleases during nucleic acid purification, helping support DNA and RNA recovery.

02

Molecular Diagnostics

Suitable for PCR, qPCR, RT-PCR and molecular diagnostic workflows requiring high-purity nucleic acid preparation.

03

Genetic Diagnostic Kits

Used in sample pretreatment and nucleic acid extraction processes for genetic testing applications.

04

Biopharmaceutical Processing

Supports removal of protein impurities during preparation and purification of biological products, including nucleic acid-based therapeutics.

05

Tissue & Cell Sample Preparation

Facilitates extraction of non-protein components from biological samples through efficient protein digestion.

KEY PRODUCT PARAMETERS

Performance & Storage Information

CONCENTRATION
20 mg/mL
SPECIFIC ACTIVITY
≥30 U/mg
SHIPPING
2–8°C
STORAGE
−25°C to −15°C
GMP grade • No detectable DNase • No detectable RNase • No detectable nickase
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